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This form occurs most frequently in growing and finishing pigs. Outbreaks may be related to stressful conditions, such as extreme heat during transportation.

Affected pigs squeal excessively when handled, require assistance to stand, and prefer to lie down soon after being forced to stand.

Affected pigs may also walk stiffly on their toes and shift weight from limb to limb when standing. Anorexia and thirst are common, and febrile pigs will often seek wet, cool areas to lie down.

Skin discoloration may vary from widespread erythema and purplish discoloration of the ears, snout, and abdomen, to diamond-shaped skin lesions almost anywhere on the body, but particularly on the lateral and dorsal regions.

The lesions may occur as discrete, pink or purple areas of varying size that become raised and firm to the touch within 2—3 days of illness.

They may disappear over the course of a week or progress to a more chronic type of lesion, commonly referred to as diamond skin disease.

If untreated, necrosis and separation of large areas of skin can occur, and the tips of the ears and tail may become necrotic and slough. Clinical disease is usually sporadic and affects individuals or small groups, but sometimes larger outbreaks occur.

Acutely affected pregnant sows may abort, probably due to the fever, and lactating sows may show agalactia. Untreated pigs may develop the chronic form of the disease, usually characterized by chronic arthritis, vegetative valvular endocarditis, or both.

Such lesions may also be seen in pigs with no previous signs of septicemia. Valvular endocarditis is most common in mature or young adult pigs and is frequently manifest by death, usually from embolism or cardiac insufficiency.

Chronic arthritis, the most common form of chronic infection, produces mild to severe lameness. Affected joints may be difficult to detect initially but eventually become hot and painful to the touch and later visibly enlarged.

Dark purple, necrotic skin lesions that commonly slough may be seen. Mortality in chronic cases is low, but growth rate is retarded. At necropsy, acutely infected pigs may exhibit skin lesions, enlarged and congested lymph nodes, edematous and congested lungs, splenomegaly, and hepatomegaly.

Petechial hemorrhages may be seen on the kidneys and heart. In chronic erysipelas, valvular endocarditis is seen as proliferative, granular growths on the heart valves, and embolisms and infarctions may develop.

Arthritis may involve joints of one or more legs, and the intervertebral articulations may be involved. Affected joints may be enlarged, with proliferative, villous synovitis and increased viscosity of synovial fluid, inflammatory exudates, and thickening of the joint capsule.

Proliferation and erosion of articular cartilage may result in fibrosis and ankylosis of the joint. Diagnosis of erysipelas is based on clinical signs, gross lesions, response to antimicrobial therapy, and demonstration of the bacterium or DNA in tissues from affected animals.

Acute erysipelas can be difficult to diagnose in individual pigs showing only fever, poor appetite, and listlessness.

However, in outbreaks involving several animals, the presence of skin lesions and lameness is likely to be seen in at least some cases and would support a clinical diagnosis.

Rhomboid urticaria or diamond skin lesions are almost diagnostic when present; however, similar lesions can also be seen with classical swine fever virus infection, Actinobacillus suis septicemia, or the porcine dermatitis and nephropathy syndrome.

Isolation of E rhusiopathiae from blood of affected pigs, especially after enrichment, is possible in acute cases and helps establish a diagnosis.

Recently, immunohistochemical methods to demonstrate the organisms in formalin-fixed paraffin-embedded tissues have become available and are useful in cases when pigs have been treated with antimicrobials before sample submission.

A rapid, positive response to penicillin therapy in affected pigs supports a diagnosis of acute erysipelas because of the sensitivity of the organism to penicillin.

Chronic erysipelas can be difficult to definitively diagnose. Arthritis and lameness, coupled with the presence of vegetative valvular endocarditis postmortem, may support a presumptive diagnosis of chronic erysipelas.

However, these lesions can be caused by other infectious agents. A positive culture of valvular vegetations or demonstration of E rhusiopathiae DNA in the lesions by PCR is definitive for diagnosing chronic erysipelas.

Serologic tests cannot reliably diagnose erysipelas but can be useful to determine previous exposure or success of vaccination protocols, because antibody titers should increase after vaccination.

Differential diagnoses to consider include conditions that can precipitate gross lesions suggestive of acute septicemia.

Septicemic salmonellosis due to Salmonella Choleraesuis infection, classical swine fever due to pestivirus infection, and septicemia and endocarditis due to Streptococcus suis infection should be considered, based on similarity of lesions.

Similar skin lesions can be found with porcine dermatitis and nephropathy syndrome caused by porcine circovirus, or infection with classical swine fever virus or Actinobacillus suis.

Early treatment with appropriate antibiotics, particularly penicillin, generally leads to recovery. E rhusiopathiae is sensitive to penicillin.

Ideally, affected pigs should be treated at hour intervals for a minimum of 3 days, although longer durations of therapy may be necessary to resolve severe infections.

On an economic basis, penicillin is the best choice for antibiotic therapy, but ampicillin and ceftiofur also yield satisfactory results in acute cases.

When injecting large numbers of affected pigs is impractical, tetracyclines delivered in the feed or water may be useful. Fever associated with acute infections can be managed by administration of NSAIDs such as flunixin meglumine or by delivery of aspirin in the water.

Erysipelas antiserum is described as an effective adjunct to antibiotic therapy in treating acute outbreaks but is not commonly available.

Treatment of chronic infections is usually ineffective and not cost effective. Vaccination against E rhusiopathiae is very effective in controlling disease outbreaks on swine farms and should be encouraged.

It may not be as effective in preventing chronic arthritis, however. Cessation of vaccination on some farms has been linked to disease outbreaks.

Injectable bacterins and attenuated, live vaccines delivered via the water are available and provide extended duration of immunity.

Optimal timing of vaccination may vary from farm to farm. When E rhusiopathiae is endemic in the production environment, vaccination should precede anticipated outbreaks.

Susceptible pigs may be vaccinated before weaning, at weaning, or several weeks after weaning. Male and female swine selected for addition to the breeding herd should be vaccinated with a booster 3—5 weeks later.

Thereafter, breeding stock should be vaccinated twice yearly. Improves lymphatic drainage. Stimulates collagen production. Each of the ten steps is carefully customised your individual needs, allowing this unique treatment to effectively combat acne, pimples, and anti-ageing.

It begins with a cleanse to gently remove any makeup, and your skin is prepared with a granular exfoliant and anti-oxidising steam. Your technician then thoroughly applies a diamond-tipped microdermabrasion to extract dead skin and debris while stimulating collagen production to restore elasticity.

If your skin is clogged, extractions are performed to clear and improve your skin. After careful assessment, a customised peel is applied to further enhance your treatment results.

An advanced hydrating solution is also applied, with a soothing lymphatic eye massage to help drain toxins and leave you feeling refreshed.

Our most advanced microdermabrasion treatment to date — your results will speak for themselves. If your skin is feeling dull, dehydrated or just a little lacklustre then sit back, relax and reawaken your complexion with our 8-step Diamond Microdermabrasion.

This non-invasive treatment will provide you with a deeper exfoliation to brighten and cleanse the skin, leaving you feeling fresh and in control of your skin health.

Please note: this treatment does not include the extractions, post-peel or eye massage found in the High Performance Microdermabrasion. Easy to squeeze in on your lunch break or between appointments, this minute express cleansing microderm includes a double cleanse, hylaceutical softening facial scrub and a diamond gold standard microdermabrasion to keep the skin looking healthy and fresh.

A microdermabrasion is a non-invasive skin treatment that exfoliates and removes the dead, dull, outermost layer of skin.

Often referred to as a micro or microderm, this gentle and invigorating treatment leaves your skin clean, clear, bright and purified.

Microdermabrasions are different to a regular facial, as they use active skin care products and advanced technology to exfoliate the dull, dead, outer surface of the skin, leaving it clear, bright and purified.

Most notably, microdermabrasion treatments feature the use of diamond-tipped machines and vacuum suction to extract debris from your pores and collect dead skin.

Australian Skin clinics offer a selection of time options and treatment types to suit your lifestyle. Treatments can range from a minute express treatment to a minute High Performance Microderm, depending on how intensive you want your treatment experience to be.

As a walk in, walk out treatment, you can even enjoy a microdermabrasion during your lunch break! Microdermabrasions are a non-invasive treatment that targets the outermost layers of the skin.

The diamond-tipped suction machine feels like tiny sand-like particles running across your face; a strange sensation for first timers but by no means painful.

A minimum series of three treatments is recommended for best results. For acne sufferers, regular fortnightly or monthly treatments can give you long-term control over your skin and breakouts.

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Possible clinical manifestations are cutaneous erythema, including characteristic diamond-shaped lesions, septicemia, arthritis, and endocarditis.

Erysipelas is a common cause of carcass condemnation at abattoirs. Diagnosis is by bacterial culture from fresh tissues, fluid, or blood or by molecular testing ie, demonstration and identification of E rhusiopathiae.

E rhusiopathiae is susceptible to beta-lactam antibiotics, and penicillin is the most commonly recommended treatment. Vaccines are generally effective in preventing acute disease.

Infectious disease caused by E rhusiopathiae in pigs is known as erysipelas and is one of the oldest recognized diseases that affect growing and adult swine.

The organism commonly resides in the tonsillar tissue. These typical healthy carriers can shed the organism in their feces or oronasal secretions and are an important source of infection for other pigs.

Infection is by ingestion of contaminated feed, water, or feces and through skin abrasions. When ingested, the organism can survive passage through the hostile environment of the stomach and intestines and may remain viable in the feces for several months.

On farms where the organism is endemic, pigs are exposed naturally to E rhusiopathiae when they are young.

Maternal-derived antibodies provide passive immunity and suppress clinical disease. Older pigs tend to develop protective active immunity as a result of exposure to the organism, which does not necessarily lead to clinical disease.

Recovered pigs and chronically infected pigs may become carriers of E rhusiopathiae. Healthy swine also may be asymptomatic carriers.

Disease outbreaks may be acute or chronic, and clinically inapparent infections also occur. Acute outbreaks are characterized by sudden and unexpected deaths, febrile episodes, inappetence, painful joints, and skin lesions that vary from generalized cyanosis to the often-described diamond skin rhomboid urticaria lesions.

Chronic erysipelas tends to follow acute outbreaks and is characterized by enlarged joints and lameness. A second form of chronic erysipelas is vegetative valvular endocarditis.

Pigs with valvular lesions may exhibit few clinical signs; however, when exerted physically they may show signs of respiratory distress, lethargy, and cyanosis, and possibly suddenly succumb to the infection.

The acute and chronic forms of swine erysipelas may occur in sequence or separately. Pigs that succumb to the acute septicemic form may die suddenly without previous clinical signs.

This form occurs most frequently in growing and finishing pigs. Outbreaks may be related to stressful conditions, such as extreme heat during transportation.

Affected pigs squeal excessively when handled, require assistance to stand, and prefer to lie down soon after being forced to stand.

Affected pigs may also walk stiffly on their toes and shift weight from limb to limb when standing. Anorexia and thirst are common, and febrile pigs will often seek wet, cool areas to lie down.

Skin discoloration may vary from widespread erythema and purplish discoloration of the ears, snout, and abdomen, to diamond-shaped skin lesions almost anywhere on the body, but particularly on the lateral and dorsal regions.

The lesions may occur as discrete, pink or purple areas of varying size that become raised and firm to the touch within 2—3 days of illness. They may disappear over the course of a week or progress to a more chronic type of lesion, commonly referred to as diamond skin disease.

If untreated, necrosis and separation of large areas of skin can occur, and the tips of the ears and tail may become necrotic and slough. Clinical disease is usually sporadic and affects individuals or small groups, but sometimes larger outbreaks occur.

Acutely affected pregnant sows may abort, probably due to the fever, and lactating sows may show agalactia.

Untreated pigs may develop the chronic form of the disease, usually characterized by chronic arthritis, vegetative valvular endocarditis, or both.

Such lesions may also be seen in pigs with no previous signs of septicemia. Valvular endocarditis is most common in mature or young adult pigs and is frequently manifest by death, usually from embolism or cardiac insufficiency.

Chronic arthritis, the most common form of chronic infection, produces mild to severe lameness. Affected joints may be difficult to detect initially but eventually become hot and painful to the touch and later visibly enlarged.

Dark purple, necrotic skin lesions that commonly slough may be seen. Mortality in chronic cases is low, but growth rate is retarded. At necropsy, acutely infected pigs may exhibit skin lesions, enlarged and congested lymph nodes, edematous and congested lungs, splenomegaly, and hepatomegaly.

Petechial hemorrhages may be seen on the kidneys and heart. In chronic erysipelas, valvular endocarditis is seen as proliferative, granular growths on the heart valves, and embolisms and infarctions may develop.

Arthritis may involve joints of one or more legs, and the intervertebral articulations may be involved.

Affected joints may be enlarged, with proliferative, villous synovitis and increased viscosity of synovial fluid, inflammatory exudates, and thickening of the joint capsule.

Proliferation and erosion of articular cartilage may result in fibrosis and ankylosis of the joint. Diagnosis of erysipelas is based on clinical signs, gross lesions, response to antimicrobial therapy, and demonstration of the bacterium or DNA in tissues from affected animals.

Acute erysipelas can be difficult to diagnose in individual pigs showing only fever, poor appetite, and listlessness. However, in outbreaks involving several animals, the presence of skin lesions and lameness is likely to be seen in at least some cases and would support a clinical diagnosis.

Rhomboid urticaria or diamond skin lesions are almost diagnostic when present; however, similar lesions can also be seen with classical swine fever virus infection, Actinobacillus suis septicemia, or the porcine dermatitis and nephropathy syndrome.

Isolation of E rhusiopathiae from blood of affected pigs, especially after enrichment, is possible in acute cases and helps establish a diagnosis.

Recently, immunohistochemical methods to demonstrate the organisms in formalin-fixed paraffin-embedded tissues have become available and are useful in cases when pigs have been treated with antimicrobials before sample submission.

A rapid, positive response to penicillin therapy in affected pigs supports a diagnosis of acute erysipelas because of the sensitivity of the organism to penicillin.

Chronic erysipelas can be difficult to definitively diagnose. Arthritis and lameness, coupled with the presence of vegetative valvular endocarditis postmortem, may support a presumptive diagnosis of chronic erysipelas.

However, these lesions can be caused by other infectious agents. James , mentioned that she was unhappy with the way BDSM was portrayed in Fifty Shades of Grey , which she considers "passed off an abusive relationship as an honest interpretation of the BDSM lifestyle".

She hoped to create a more nuanced view of the BDSM world with the series. The trailer for the series was released on 29 April The series debuted with low viewership of 0.

Uproxx praised the series saying, "[Submission] is trying to change the way we look at late-night erotica".

From Wikipedia, the free encyclopedia. Submission Submission promotional poster. Erotic thriller Drama. Jacky St. James Paul Fishbein.

Rotten Tomatoes. The Daily Beast. Huffington Post. Showtime original programming. Moonbase 8 Your Honor Halo Categories : s American drama television series American television series debuts American television series endings Erotic television series Showtime TV network original programming.

Hidden categories: Pages using infobox television with nonstandard dates. Namespaces Article Talk. Views Read Edit View history.

Help Learn to edit Community portal Recent changes Upload file. Download as PDF Printable version. Submission promotional poster.

Dolby Digital 5. Ashley Ashlynn Yennie is stuck in an unhappy relationship, but finally breaks up with her boyfriend. After the break-up, she moves in with her friend Jules Victoria Levine.

The next day while searching for the job she walks in on the cafetaria owner Raif Kevin Nelson and Dylan Skin Diamond having sex. She is embarrassed, but Raif ends up offering her a job as a barista.

Later she finds out that Dylan is Jules' roommate. Dylan catches Ashley reading the book and invites her to the book club to discuss the book.

Although initially hesitant, Ashley agrees. Raif tells Ashley that he thinks Dylan is crazy and reveals that she had sex in the cafeteria bathroom a few days ago with a complete stranger Sydney Black.

In the bookclub, women discuss the book and talk about their fantasies. Later that night, Ashley sees Dylan taking Chelsea, one of the book club members, handcuffed and blindfolded in her car.

She gets worried and calls Jules, but she doesn't pay attention. So she calls Raif at her home, Raif assures her that Chelsea will be fine and they end up having sex.

Dylan takes Chelsea to a dungeon, ties her up naked and blindfolded, and introduces her to Elliott Justin Berti. Elliott engages in bondage with Chelsea, which she enjoys.

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